Revealed in its USA 2015 brochure, both itineraries combine land journeys with river cruises aboard a 62-stateroom paddlewheeler, Queen of the West.
The 20-day Columbia and Snake River Cruise with West Coast USA starts in Los Angeles with a land tour to Portland before sailing from Portland to Clarkson.
The seven-night cruise will include visits to Mount St Helens, Multnomah Falls and Washington State.
Prices start from $12,995 per person twin share.
The 18-day Columbia and Snake River Cruise with Western Wilderness starts with a seven-night river cruise from Portland to Clarkston before guests take a land journey to Las Vegas via Yellowstone National Park, Salt Lake City and Bryce Canyon.
Prices start from $11,495 per person twin share.
The new brochure also includes two new land itineraries – the 18-day Frontier Land Discovery from Los Angeles to San Diego and a 15-day West Coast USA tour from Los Angeles to Seattle.
Meanwhile, the Mississippi River Cruising itineraries include new and exclusive experiences such as the chance to join a traditional Dixieland Jazz marching band through the streets of New Orleans.
The 82-page brochure is available in travel agents or click here to view it online.